Alercell Is All Set to Launch a Leukemia Diagnostic Test Lena Q51(R)

Bozeman, MT, December 29, 2022 – (SEAPRWire) – Alercell is all set to launch LENA Q51(R) in January 2023. A leukemia diagnostic test based on sequencing DNA will detect up to 51 Genes mutations in Leukemia patients. Alercell is on a mission of making a significant difference in the fight against cancer by offering unique and precise diagnostic solutions that enhance patient outcomes. Alercell is a young and dynamic firm. To better fulfill the demands of the clients, they are continually working to improve their products and services. They have an active research and development program to create new goods for even more precise testing, and their products are based on the most recent technology. Alercell, Inc. seeks to provide innovative in-vitro testability for cancer testing while streamlining the process of detecting infectious diseases. In their ideal world, early disease detection is achieved by testing, allowing prompt implementation of preventative measures. Alercell is based in the United States, but they also have manufacturing and storage facilities in Europe and Asia, extending its accessibility and reach around the globe. In July 2020, the first Alercell COVID-19 fast test arrived in the USA. Since then, Alercell has created a stir in the sector by creating new, creative methods for conducting tests that are more precise, effective, and easily accessible. Being a molecular diagnostics startup, Alercell, Inc. also offers quick testing for leukemia and cancer to detect life-threatening conditions as soon as possible. The company was established to give cancer patients worldwide better precise and rapid diagnostic tools. By offering unique and accurate diagnostic solutions that enhance patient outcomes, Alercell aims to contribute to the fight against cancer. “Stopping it before it starts” is the cornerstone of the Alercell mission. Our genetic testing is the first defense against cancer, leukemia, and infectious diseases. Bozeman, Montana-based Alercell is a biotechnology business with a R&D branch in New York City. Alercell will soon introduce a new test and brand. The first leukemia diagnostic test, LENA Q51®, was based on DNA sequencing and could identify up to 51 gene alterations in leukemia patients. An intriguing development is this test. Until recently, a series of blood tests and a bone marrow biopsy were required when someone was “suspected” to have leukemia. It costs thousands of dollars and takes somewhere between 6 and 9 weeks. With LENA Q51®, all of this is avoided, and in just three hours using a qPCR machine, clinicians will be able to identify any gene mutations among 51 different genes. By doing this, we can determine in 3 hours via computer, eliminating the need for human interpretation; the information gathered will also enable us to tailor the patient’s treatment—all of this for a much lower price. Moreover, the fight against the most lethal cancer, lung cancer in the US is a first. The first methylation-based molecular diagnostic test for lung cancer, LENA S1®, will be made available by Alercell later in the first quarter of 2023. As an epigenetic regulator of gene expression, DNA methylation enables early diagnosis of lung cancer and very accurate localization of the disease, if present. Alercell Neuroscience will make a formal announcement in early 2023. Alercell Neuroscience aims to create a nanoparticle neural interface for recording and controlling brain activity. Prof. Gleb Sukhorukov, Ph.D., Chair in Biopolymers at the School of Engineering and Materials Science, Queen Mary University of London (QMUL), will spearhead our efforts. Professor Sukhorukov is a renowned scientist around the globe. Alercell plays a significant role in preventative medicine, particularly in the detection and treatment of cancer. The CEO and the CMO of the company, Dr. Alexandre Scheer MD, are leveraging genetic research to develop novel drugs and testing procedures. Scheer thinks that genetic science holds the answer to improving early diagnosis and eventually identifying severe illnesses before they manifest inside the body. By employing such techniques, the healthcare system may save a large sum of money, and patients may receive excellent care before grueling chemotherapy treatments. Scheer is particularly sensitive to this subject since he is undergoing all these challenging therapies while battling severe cancer. Frederic Scheer stated, “I want to let people know well in advance to avoid what I am going through”. Alercell, Inc. co-founder Frederic Scheer successfully floated multiple start-up firms on stock-exchanges including NASDAQ and NYSE. For the past 25 years, he has worked in the chemical business and alternative technology. Scheer holds 15 US biotechnology patents including three on nanoparticles. As the co-founder of Alercell Inc. “I am thrilled that via the application of our knowledge of the genome, we are now able to produce very performing tests that will help people in finally avoiding the unpleasant traditional treatment,” he says regarding the company’s goods. The business focuses on collaborating with reputed pharmaceutical firms and other healthcare organizations to benefit its patients and ensure that the public always has access to the quickest diagnostic procedures and most affordable medications.” Media Contact Brand: ALERCELL, INC. Contact: Frederic Scheer E-Mail: fscheer@alercell.com Website: https://alercell.com SOURCE: ALERCELL The article is provided by a third-party content provider. SEAPRWire ( https://www.seaprwire.com/ ) makes no warranties or representations in connection therewith. Any questions, please contact cs/at/SEAPRWire.com Sectors: Top Story, Daily News SEA PRWire: PR distribution in Southeast Asia (Hong Kong: AsiaExcite, EastMud; AsiaEase; Singapore: SEAChronicle, VOASG; NetDace; Thailand: SEAsiabiz, AccessTH; Indonesia: SEATribune, DailyBerita; Philippines: SEATickers, PHNotes; Malaysia: SEANewswire, KULPR; Vietnam: SEANewsDesk, PostVN)
More

开拓药业新型C-Myc-GSPT1双靶点降解剂GT19715最新数据以口头报告亮相ASH 2022

EQS 新闻 via SEAPRWire.com / 2022-11-10 / 10:09 UTC+8 开拓药业新型C-Myc-GSPT1双靶点降解剂GT19715最新数据以口头报告亮相ASH 2022 北京时间2022年11月10日,开拓药业(股票代码:9939.HK),一家专注于潜在同类首创和同类最佳创新药物研发及产业化的生物制药公司,宣布其自主研发的新型C-Myc/GSPT1双靶点降解剂GT19715的最新研究结果已获选2022年美国血液学会年会(American Society of Hematology,ASH 2022)的口头报告,相关摘要可在ASH官网上查阅。 美国血液学会年会是全球血液学领域最大的国际盛会,每年吸引汇集了血液学的基础、转化和临床研究人员。ASH 2022将于2022年12月10日(周六)至12月13日(周二)在美国路易斯安那州新奥尔良举行。 在70%的人类癌症中存在癌蛋白Myc失调,主要表现为表达水平增加和活性增强,以促进癌症(包括白血病和淋巴瘤) 的进展。MYC基因重排在Burkitt淋巴瘤(BL)中的易位最为常见(100%)。在急性髓系白血病(AML)中也观察到MYC的高表达,包括带有TP53突变或venetoclax (ven)耐药的AML患者。尽管最近AML的治疗手段取得了很大的进展,这两种AML患者都有非常差的临床预后。 开拓药业联合美国德克萨斯大学MD安德森癌症中心白血病学教授Michael Andreeff团队,研究了同类首创的新型C-Myc/GSPT1双靶点降解剂GT19715在耐药AML模型中的临床前活性。 研究人员利用单细胞质谱流式技术,发现与正常骨髓CD34+细胞相比,低分化的CD34+ AML细胞中的c-Myc蛋白水平增加。GT19715在具有TP53突变的AML细胞中,特别是在低分化的CD34+细胞中,显示出很好的抗白血病效果;以及在Daudi Burkitt淋巴瘤和venetoclax耐药AML模型小鼠中,GT19715治疗消除了淋巴瘤和白血病细胞。该研究结果将由Michael Andreeff团队的Yuki Nishida博士于2022年12月10日进行口头报告。 开拓药业创始人、董事长兼首席执行官童友之博士表示,“我们非常高兴新型c-Myc/GSPT1双靶点降解剂GT19715的最新研究结果被选为今年ASH年会的口头报告,这表明国际血液学界对GT19715治疗潜力的认可。我们将加快推动GT19715进入临床阶段的进程,希望为未满足需求的患者带来更多创新的治疗选择。” Andreeff博士表示,“我们非常高兴在今年ASH年会上展示GT19715的临床前活性数据,特别是在MYC驱动的白血病和淋巴瘤中。MYC控制着各种癌症起始和进展的致癌程序,尽管有许多针对MYC或其通路的尝试,长期以来其一直是癌症治疗中“不可成药”的靶点之一。我们去年在ASH年会中报告了p53重新激活对MYC的抑制作用,但现在有了第一个成功降解MYC本身的化合物,显示出非常有潜力的早期活性,应该也适用于其他MYC驱动的恶性肿瘤。” ■ 口头报告 摘要标题: C-MYC Targeting By Degradation: Novel Dual c-Myc/GSPT1 Degrader GT19715 Induces TP53-Independent Cell Death in Acute Myeloid Leukemia and Lymphomas 降解靶向C-MYC:新型C-MYC/GSPT1双靶点降解剂GT19715诱导急性髓系白血病和淋巴瘤中TP53非依赖性细胞死亡 摘要编号:199 分会场:604,Molecular Pharmacology and Drug Resistance: Myeloid Neoplasms: Targeted Protein Degradation and Emerging Small Molecule Inhibitors in Myeloid Neoplasms分子药理学和耐药性:髓系肿瘤:靶向蛋白降解和髓系肿瘤中新出现的小分子抑制剂 报告形式:口头报告 报告时间:美国东部时间2022年12月10日下午2点 摘要链接:https://ash.confex.com/ash/2022/webprogram/Paper164968.html 关于开拓药业 开拓药业成立于2009年,专注发展潜在“best-in-class”和“first-in-class”创新药物的研发及产业化,致力成为创新疗法研究、开发及商业化的领军企业。公司经过多年的发展,以雄激素受体(AR)相关疾病为核心,研发多通道产品组合,产品覆盖全球高发病率癌症及其它未满足临床需求的疾病领域,包括新冠肺炎、前列腺癌、乳腺癌、肝癌、脱发和痤疮等。开拓药业前瞻性布局了包含小分子创新药、生物创新药及联合疗法的多元化产品管线,包括7款正在开展临床研究的产品,如两款雄激素受体(AR)拮抗剂、ALK-1单抗、AR-PROTAC化合物、PD-L1/TGFβ双靶点抗体、mTOR激酶靶向抑制剂和Hedgehog抑制剂,以及正在进行临床前研究的ALK-1/VEGF双抗和c-Myc抑制剂等。公司在全球拥有已获得及申请中的110多项专利,多个项目被列为国家十二五、十三五“重大新药创制”专项。2020年5月22日,开拓药业正式在香港联合交易所有限公司主板挂牌上市,股票代码:9939.HK。欢迎访问公司网站:www.kintor.com.cn 文件: 开拓药业新型C-Myc-GSPT1双靶点降解剂GT19715最新数据以口头报告亮相ASH 2022 2022-11-10 此财经新闻稿由EQS Group via SEAPRWire.com转载。本公告内容由发行人全权负责。原文链接: http://www.todayir.com/sc/index.php
More